Best Pain Relief Medicines
Considering my website is an homage to medicine derived from plants I would be remiss to point out that nature and science have developed amazing pain killers. I love to study Homeopathy but I am not an expert and no advice represented in this small personal blog of mine should ever be replaced by advice given by a qualified medical doctor.
Cannabis and CBD oil
In my opinion the best gentle pain reliever is Cannabis. Though its illegal to grow and use cannabis in many places however lots of countries are now seeing the advantages of medical cannabis. In particular CBD oil has been shown to positively influence out come of seizures and pain relief. CBD oil is only product from our list that is available directly via online from well known vendors like Amazon and ICEHeadShop.
Hydrocodone is an antitussive (cough suppressant) and narcotic analgesic agent for the treatment of moderate to moderately severe pain. Studies indicate that hydrocodone is as effective, or more effective, than codeine for cough suppression and nearly equipotent to morphine for pain relief.
Hydrocodone is the most frequently prescribed opiate in the United States with more than 136 million prescriptions for hydrocodone-containing products dispensed in 2013 and with nearly 65.5 million dispensed in the first six months of 2014 (IMS Health™). There are several hundred brand name and generic hydrocodone products marketed, most of which are combination products. The most frequently prescribed combination is hydrocodone and acetaminophen.
Morphine is obtained from the seedpod extract or opium found in the poppy plant, Papaver somniferum. Morphine is widely used in clinical pain management, especially for terminal cancer pain and post-surgery pain. In the body, morphine has several effects including reduction of pain, loss of hunger, and suppression of cough.
Once injected or ingested, morphine enters the blood stream which carries it to the brain and other parts of the body where it activates opioid receptors to exert the effects of the drug. Activation of the μ1 receptor subtype leads to pain relief, while activation of the μ2 receptor can cause effects such as respiratory depression and addiction. Sedation or sleepiness is caused by morphine’s activation of the κ receptor subtype.
Morphine is categorized as a “Schedule 2 Drug” by the Drug Enforcement Agency (DEA). This drug category means that while morphine has accepted uses for medical treatment, its use is severely restricted, as it has a high potential for leading to strong psychological or physical.
Fentanyl is a powerful pain-relieving drug, 50 times more potent than morphine. It belongs to a group of drugs known as opioids. It is prescribed for the chronic, severe pain as a result of cancer, nerve damage, back injury, major trauma or other causes. Fentanyl is also used to help people deal with cancer pain. Some forms of fentanyl are very fast-acting. People suffering from chronic pain may be provided with patches that release the drug over 24 to 72 hours. Fentanyl is also offered in sublingual film – in other words, a small sheet of film that is intended to be placed under the tongue where it will dissolve.
Fentanyl rapidly crosses the blood-brain barrier. It is similar to other μ-opioid receptor agonists (like morphine or oxycodone) in its pharmacological effects and produces analgesia, sedation, nausea, vomiting, itching, and respiratory depression. Fentanyl appears to produce muscle rigidity with greater frequency than other opioids. Unlike some μ-opioid receptor agonists, fentanyl does not cause histamine release and has minimal depressant effects on the heart.
Oxycodone is a moderately priced drug used to treat moderate to severe pain. It is medication—an opioid drug, like morphine, codeine and methadone.
It is found in several products:
- in combination with other drugs, in products such as Percocet, Oxycocet and Endocet
- by itself in immediate-release (IR) products, such as Oxy-IR
- by itself in controlled-release (CR) products, such as OxyContin (no longer available), OxyNEO, Apo-Oxycodone CR and PMS-Oxycodone CR.
Oxycodone products can be helpful to people with severe pain when taken as prescribed, but they can be very dangerous. For someone with little or no tolerance to opioids, swallowing oxycodone, especially more pills than you are used to, could cause you to overdose.
The risk increases when people looking for a “rush” tamper with the controlled release by crushing or chewing the pill, or crushing and dissolving the pill for injection, causing all of the oxycodone to be released at once.
Codeine is considered a ‘weak’ opioid pain medication, and is in the same family of medicines as opioid pain medications and drugs such as morphine, oxycodone and heroin. In the body codeine is converted into morphine, which is thought to be responsible for almost all of the pain relieving effects of codeine.
Codeine works by stopping pain signals from travelling along the nerves to the brain. This leads to a decrease in the way you feel pain and your reaction to pain. Codeine is available on a prescription from a doctor.
Follow all directions on your prescription label. Codeine can slow or stop your breathing. Never use this medicine in larger amounts, or for longer than prescribed. Tell your doctor if the medicine seems to stop working as well in relieving your pain.
Codeine may be habit-forming, even at regular doses. Never share this medicine with another person, especially someone with a history of drug abuse or addiction.
Buprenorphine, a medication for addiction treatment and pain relief, has also been found to dramatically decrease death rates from opioid overdose. Only 10% of patients needing treatment, however, have access to the medication.
This new medication’s unique pharmacological characteristics provide for less respiratory depression or overdose risk than opioids such as morphine, heroin, methadone, and oxycodone, as well as milder manifestations of withdrawal upon cessation. This wide safety margin makes buprenorphine suitable for use in new treatment settings, such as office practices, as well as more traditional opioid treatment programs.
Further supporting this versatility, buprenorphine can be effective when taken every other day or less frequently, and it is supplied in a combined formulation with naloxone that is designed to reduce its potential for abuse.